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Antidepressants – Risk vs. Benefit

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http://www.sugaredstyle.com.au/?seltork=Binary-options-bully-forex-peace-army-oanda&08c=87 According to Vice Chair in the Department of Psychiatry and Behavioral Sciences and Director of Child and Adolescent Psychiatry at the University of Texas Medical Branch at Galveston, Karen Dineen Wagner, M.D. states that two recent publications by Gibbons and colleagues have provided the medical community with information regarding the risk to benefit ratio of antidepressants for the treatment of major depressive disorder (MDD) in youth, adults, and elderly.[1] Wagner discusses such in her article “Antidepressants: Risk vs. Benefit in Depression.”

Köp Cialis på nätet Gällivare First of all, Gibbons and colleagues sought to examine the benefits of certain antidepressants in order to determine whether there were differences in the response rates based on the depression severity.[2] They asked: Do patients with mild and moderate depression benefit more from antidepressants than patients with severe depression?2 To reach an answer, Gibbons and colleagues conducted a study that included the antidepressants fluoxetine and venlafaxine. Regarding fluoxetine, four youth studies of 708 patients were conducted, as well as 12 adult studies of 2,365 patients, and four geriatric studies of 960 patients.2 With venlafaxine IR (immediate release), there were 11 adult studies of 2,421 patients, and with venlafaxine ER (extended release) there were 10 adult studies of 2,461 patients.2 There were no youth or geriatric studies with venlafaxine IR or ER. Gibbons and colleagues measured youth depression using the Children’s Depression Rating Scale-Revised (CSRS-R), and they measured adult and geriatric depression using the Hamilton Depression Rating Scale (HAM-D).2 Response to antidepressants was defined as a 50 percent reduction in the CDRS-R at week six for children and a 50 percent reduction in the HAM-D at week six for adults and elderly.2

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