Effectiveness of Medicines to Treat Alcohol Use Disorders
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A recent analysis of more than 120 studies that examined the effectiveness of medicines to treat alcohol use disorders found that acamprosate and oral naltrexone have the strongest evidence for decreasing alcohol consumption.
Alcohol use disorders (AUDs) are too common, causing serious illnesses and increasing the risk of early death by three times.1
Treating AUDs is difficult; however, when treated with medicine, many do well.1
Unfortunately, less than 10 percent of patients with AUDs receive medicine to assist in reducing alcohol consumption.1
Daniel E. Jonas, MD, MPH, and colleagues of the University of North Carolina conducted a review and meta-analysis to evaluate both the benefits and harms of medicines that are used for the treatment of adults with AUDs.1 Overall, the researchers identified 122 randomized clinical trials and one cohort study, giving a total of 22,803 participants.1